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grin007 [14]
4 years ago
11

Please help me find the answer

Biology
1 answer:
alukav5142 [94]4 years ago
7 0

Basically, you need to know that the leading strand is synthesized faster and without any breaks, but the lagging strand is synthesized more slowly and in fragments. Both new DNA strands are synthesized by DNA Polymerase going from 3' → 5' direction on the template strand and therefore synthesizing the new strand in the 5' → 3' direction.

If you want to try to understand why that is, here's my best shot:

<em>Disclaimer: "Something about this topic was incredibly hard for me to conceptualize all throughout high school and college. I did not understand why Okazaki fragments formed until I started teaching and HAD to be able to explain it.</em>

<em />

Think of DNA polymerase (the enzyme constructing the new strands of DNA) as one of those wind up toys that can only move forward (***see attached pic of yellow smiley face toy***). Like the toy, DNA Polymerase can only move down the template strand of DNA in the 3' → 5' direction (synthesizing the new strand in the 5' → 3' direction). Well, the two strands of DNA that have to be replicated actually run in opposite directions of each other. Therefore, one strand (leading strand) will be replicated relatively quickly and straightforward, while the other strand (lagging strand) will have to be synthesized backwards...but the catch is that just like our little wind-up toy DNA polymerase cannot move backwards. So, instead it must wait for DNA helicase to "unzip" a section of the DNA, and then it will start synthesizing new DNA from the point nearest the DNA helicase in the opposite direction from which DNA helicase is moving. DNA polymerase will eventually get to the beginning of the DNA strand, so it will then detach and reattach at the point nearest to the DNA helicase and start synthesizing another fragment again in the opposite direction from which DNA helicase is moving (until it gets to the start of the first fragment and the process begins again). Think of it as having to pick up our little wind-up toy and move it further along in its journey to the other side of the table because it's facing backwards and keeps walking in the opposite direction that we want it to go.

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A command economy is one in which a centralized government controls the means of production. The government determines what is produced, how it is produced and how it is distributed. Private enterprise does not exist in a command economy. The government employs all workers and unilaterally determines their wages and job duties. There are advantages and disadvantages of command economy structures. Command economy advantages include low levels of inequality and unemployment and the common good replacing profit as the primary incentive of production. Command economy disadvantages include lack of competition and lack of efficiency.
A command economy is one in which a centralized government controls the means of production. The government determines what is produced, how it is produced and how it is distributed. Private enterprise does not exist in a command economy. The government employs all workers and unilaterally determines their wages and job duties. There are advantages and disadvantages of command economy structures. Command economy advantages include low levels of inequality and unemployment and the common good replacing profit as the primary incentive of production. Command economy disadvantages include lack of competition and lack of efficiency.
Unlike the invisible hand of the free market, which cannot be manipulated by a single company or individual, a command economy government can set wages and job openings to create an unemployment rate and wage distribution that it sees fit.
Whereas the motivation for profit drives most business decisions in a free market economy, it is a non-factor in a command economy. A command economy government, therefore, can tailor products and services to benefit the common good without regard to profits and losses. For example, most true command economy governments, such as Cuba, offer free, universal health care coverage to their citizens.
Command economies sit at a disadvantage as their inherent lack of competition hinders innovation and keeps prices from resting at an optimal level for consumers. Although those who favor government control criticize private firms that esteem profit above all else, it is undeniable that profit is a great motivator and drives innovation. For this reason, most advancements in medicine and technology have come from countries with free market economies, such as the United States and Japan.

Efficiency is also compromised when the government acts as a monolith, controlling every aspect of a country's economy. The nature of competition forces private companies in a free market economy to minimize red tape and keep operating and administrative costs to a minimum. If they get too bogged down with these expenses, they achieve lower profits or have to raise prices to meet expenses; ultimately, they are driven out of the market by competitors capable of operating more efficiently. Production in command economies is notoriously inefficient as the government feels no pressure from competitors or price-conscious consumers to cut costs or streamline operations.



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