The properties of gamma which paved its way to the area of medicine are having high energy of all the waves in the spectrum. With this they can penetrate into almost all surfaces. One application would be its use in killing cancer cells and to examine the internals of the body.
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ya it can also be the largest compound but it needs alot if pressure
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The important point is that the surface area to the volume ratio gets smaller as the cell gets larger. Thus, if the cell grows beyond a certain limit, not enough material will be able to cross the membrane fast enough to accommodate the increased cellular volume.