The frontier posed many dangers to the pioneers. There were indians, brutal winters, outlaws, and many more. Having neighbors gave the pioneers help if there was a situation that couldn't be handled alone. Neighbors could help each other with workd that needed to be done. Much of the time the nearest town was 50-100 (or more) miles away. When you had neighbors you had friends. You had someone that could ride for help when you couldn't go yourself
In many ways the Columbian Exchange that occurred after Columbus landed in the New World was an early form of globalization in that it led to good and ideas to be spread over the world.
