The best and most correct answer among the choices provided by your question is the fourth choice or letter D.
The most effective thesis sentence from the given choices is: <span>Valuable lessons are important in life.</span>
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The answer is most likely four. Anne and her best friend Ellen, had to fake sleep when the Nazis INVADED THEIR HOME and Ellen had to hide her necklace. Whenever they heard about there brother-in-law getting killed, it affected them. And Anne had to hide from the Nazis at one point to not get caught.
