In human gene therapy, a genetically modified virus (a.k.a. a viral vector) can alter the genetic variation of a cell, but not all viral vectors do.
The process often begins with the delivery of or creation of a segment of viral double stranded DNA (containing the gene you want to introduce). Then typically an enzyme known as an integrase cuts the ends of the segment of viral DNA and also cuts open the cell's DNA. Then the viral DNA is integrated/ inserted into the cell's DNA. The connecting ends are ligated together and adjusted so that the nucleotide base pairs match up.
This in the future may affect the gene pool for instance if the viral DNA (your gene) was inserted in the middle of another gene or important regulatory sequence of the cell DNA, and this alteration may be passed on into offspring and become present in the gene pool, which could have bad effects.
The effects on the gene pool really depends on what the virus ends up doing. For example, it may fix the function of a damaged gene which is the goal, and allow for a working gene to be in the gene pool, which would be good. The problem with gene therapy is that it's difficult to predict 100% what the virus will do every time it is given to a patient.
But it's very important to consider that it will only affect the gene pool if the virus is able to enter and alter germ cells (reproductive cells). If the virus, enters somatic cells (regular body cells) this will not be passed on to future generations. So viruses can be designed to avoid germ cells and avoid this gene pool issue. Also, some viral vectors use viruses that do not integrate their DNA, the cells just express the viral DNA (create the desired protein from it) and over time the viral DNA is degraded/ lost which wouldn't pose this threat.
This is long, but I hope it helped!
Capture myopathy is a heart condition in animals specifically in tamarins. Dr Natterson-Horowitz studied the condition and discovered that it is similar to cardiomyopathy which is a heart condition in humans. She also studies some conditions that are parallel to both humans and animals.<span />
Pia mater
<span>Pia mater is a highly vascular tissue that cleaves
firmly to the surface of the brain and spinal cord. Pia mater protects the
central nervous system by nourishing the brain and allowing blood vessels to
pass through it. The inflammation of the pia mater can lead to meningitis</span>
Answer:
The forensic autopsy is preformed by "Forensic pathologist".
Explanation:
The forensic pathologist would perform a forensic autopsy, Forensic pathologist will focus on the cause behind the death by studying the body or the corpse. Most probably they do the postmortem examination. The forensic pathologist is also a medical doctor, who must have completed the training in anatomical pathology with specialization in forensic pathology. The forensic pathologist are basically there to find the cause and also the manner of death. They are trained for performing autopsy, helps in evaluation of historical and law enforcement investigative information, documentation in sexual assault, helps in collection of the medical evidence.
Answer:
Glycolysis produces pyruvate, ATP, and NADPH by oxidizing glucose. During cellular respiration, glucose combines with oxygen to form carbon dioxide, water, and ATP.
Explanation:
