Where are all the options?
D. In all the others the book is the main point, not the author.
It could be said that Annie´s tone (lines 121-149) tends to reflect her attitude towards her situation and the people around her so in this case she sounds upset about Helen situation and it seems that she is not able to control her.
The first one is the correct way to use it, since it separates the parts of the sentence into fragments that can still be understood without changing the meaning of the entire sentence.