First, it transformed the monarchy. Second, the religion and the church. The Enlightenment Philosophers began to contest the dogma of the catholic church, which considered earthly life to be a simple passage towards eternal life. They challenged the teaching of the priests. They also changed the social and political values in society.
In my opinion and based on the researches I've done, among the four choices listed above, Jefferson's more liberal view of expanding rights for all Americans was most favored by the region of the South.
