Answer:
Vexed has several definitions:
- (of a problem or issue) difficult and much debated; problematic, "the vexed question of how much money the government is going to spend"
- annoyed, frustrated, or worried, "I'm very vexed with you!"
- make (someone) feel annoyed, frustrated, or worried, especially with trivial matters, "the memory of the conversation still vexed him'.
Macbeth drugged the guards with wine, which led to her stabbing Duncan. Afterwards she decides to frame the guards.
hope this helps
<span> A semicolon should precede the conjunctive adverb.</span>