My answer would be D, the mixing of multiple cultures in a single place.
Hope this helps
The main economic factors that encouraged the growth of slavery was the heavily agricultural basis of the South's economy, which relied very much on slave labor. The geographic location of the southern colonies also made tobacco growth, and thus a demand for slaves high.
Because he thought he had arrived to India, he was actually trying to get to Indiam he thought that traveling west would be a closer way to India, rather than traveling around Africa