From the Middle Ages the famous Silk Road was the main trade connection between Europe and Asia.
But in the 15th Century Ottomans managed to conquer the Byzantine Empire and they had the control of territory through which the trade was established.
That is why Europeans decided to find some other route to India and China.
Can you actually put the "descriptions" in your question next time best one i can give you is the north was <span>industrial, urban, and anti-slavery</span>