Although it is often claimed that Christians were persecuted for their refusal to worship the emperor, general dislike for Christians likely arose from their refusal to worship the gods or take part in sacrifice, which was expected of those living in the Roman Empire.
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In the mid-1800s, the country was divided into 3 sections: North, South, and West. The North's economy was dominated by manufacturing and industry. The South's economy was primarily agriculture with a heavy focus on growing cash crops like cotton, tobacco, rice, and indigo. The West's economy was a mixture of manufacturing and agriculture. The different economies would drive wedges between the different sections and result in different societies and values.
Flocking to the U.S for jobs, opportunities, and to have a position in the new economy.