Answer:
The events in chronological order are:
- Abrin is absorbed into the blood and enters the body's cells
- Abrin binds to ribosomes in the cytoplasm
- Abrin inactivates the 28S rRNA in the large subunit of the ribosome.
- Ribosomes are unable to add new amino acids to polypeptides
- Protein synthesis halts in many tissues
- Multiple organ systems fail
- Victim dies
Explanation:
Abrin is a toxic protein obtained from the seeds of Abrus precatorius, it is highly toxic, with an estimated human fatal dose of 0.1-1 microgram/kg, and causes death after accidental and intentional poisoning.
When ingested the abrin would enter the victim's body and travel through the blood and eventually enter a cell's cytoplasm (abrin is absorbed into the blood and enters the body's cells). Once there it would interact with the ribosomes and reacts with them on a molecular level (peptide bond catalytic enzyme) (abrin binds to ribosomes in the cytoplasm), which results in the ribosome exhibiting its toxic response to abrin (abrin inactivates the 28S rRNA in the large subunit of the ribosome). As a result of the ribosome reacting to abrin (ribosomes are unable to add new amino acids to polypeptides), protein synthesis within that cell is affected (protein synthesis halts in many tissues). Once multiple cells are affected by abrin the organ will exhibit its toxic response (multiple organ systems fail), and the victim would die.
The systems are:
Nervous system: this is because the brain sends out commands to the body or it signals other parts which makes your body move like walk or to pick something up.
Muscular system: the muscular system such as your bones and muscles is what keeps the bones together so you could move/walk.
Hope this helped :)
Have a great day
<span>The troposphere is the only layer that has ozone</span>
Answer:
Hormones secreted by the hypothalamus regulate the pituitary gland
Explanation:
The hypothalamus is the region of the brain (diencephalon) of relatively small vertebrates, located on the thalamus, whose function is to maintain homeostasis, that is, the balance of internal bodily functions in adjustment to the environment, mainly through coordination between the nervous system. and the endocrine system. The hypothalamus also produces two hormones, oxytocin (OCT) and antidiuretic hormone (ADH) that are transported to the neuro pituitary where they are stored, and release hormones that regulate adenoipophysis activity and regulate the pituitary gland.
