Ruling the Byzantine Empire and providing the "bubonic plaque" or "Justinian's plaque".
Answer:
Europe was strongly encouraged by Senator Gerald P. Nye of North Dakota
The question asks to find who was Emperor Justinian's most trusted advisor, and based on my further research and my analysis on the said question. The answer would be Empress Theodora. I hope you are satisfied with my answer and feel free to ask for more if you have question and clarification
Maybe it’s B I’m not really sure so yeah