M represents units of mass, and c2 is the speed of light squared, or multiplied by itself. it is equal to energy.
the equation says that energy and mass (matter) are interchangeable; they are different forms of the same thing.
The reason how it is related to the speed of light is that energy, be it light waves or radiation, travels at the speed of light.
I think The Mathematical Jewel (1585) was his most popular and influential publication. The “Jewel” of the title was an astrolabe designed by Blagrave and considered superior for its time. The title page (shown above) proclaims the book’s contents:
The mathematical ievvel, shewing the making, and most excellent vse of a singuler instrument so called: in that it performeth with wonderfull dexteritie, whatsoeuer is to be done, either by quadrant, ship, circle, cylinder, ring, dyall, horoscope, astrolabe, sphere, globe, or any such like heretofore deuised: ...
Sonogram machines allow parents of a fetus to know the gender before birth, therefore encouraging gendercide for parents who do not desire a child of a specific gender, sometimes leading them to decide to terminate.
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