He might have contracted some tropical disease such as Malaria during his time in India, which might have proved fatal for his body, weakened by wounds during war and alcohol. His march through the Gedrosian desert, far away from water sources is what utterly 'destroyed' him.
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Soon after taking office as president, Reagan began implementing sweeping new political and economic initiatives. His supply-side economic policies, dubbed "Reaganomics", advocated tax rate reduction to spur economic growth, economic deregulation, and reduction in government spending.
Explanation:
I dont quite understand what you mean need more info
During the isolation, they managed to create a distinct cultural identity and a society that reflected their values because they did not have anything from foreign lands to affect their beliefs. They eventually met economic problems which led to the end of the isolation period and the country entered the Meiji restoration.