The best describes Henry Clay's American system of the Early 1800
is:
Called Great Comprimiser,
balance sectional interests in the missouri compromise, served as one of
the most influential speakers of teh hous, know fro his great speeches.
was a proponent of the american system .
hope that helps
No
many things could change it science , an invasion of another country etc
Native Americans and slaves were not represented in the declaration of independence.

This sentence gives no reason to add any commas what so ever. This would be a straight forward run-on sentence that would need no clause, pauses or anything that would break this sentence down any more.
Option B would give clear and straight forward information. The first option broke this sentence down as we can see, and as for this, this would not be the proper way of expressing this sentence. Therefore, your
last option would then be your answer.