It seems A would be best as it deals with frogs in that location
Although the rest of the question is not included, we can still describe what this quote means in the novel. This quote comes from the book <em>The Pearl</em> by John Steinbeck.
In this quote, Kino is describing his wife Juana. Kino has always been obsessed with manhood, and what it means to be a man. Similarly, he wants his wife to be a typical woman. Juana is indeed patient, fragile and submissive. She obeys her husband and fulfills ideals of traditional womanhood. However, she is also very strong. She is resilient, practical and brave. This semi-contradiction shocks Kino, but also allows him to rely on her for support throughout their troubles.
If you're meaning just a sentence with these two words, then:
She approached the significant hole in the wall, peering through it, a soft sigh of defeat passing her lips when she saw that the impenetrable vault she was meant to go wasn't there.
That help any?
Probably b, it seems to be the only one with an interaction. D is also technically one but in a negative way
The second article is the one that has it<span />