Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Answer:
The different possible genotypes are AA, AO, BB, BO, AB, and OO. These are derived according to the A, B and O blood group model.
The table is given below:
Blood Type Genotype
Blood Type A Genotypes AA or AO
Blood Type B Genotypes BB or BO
Blood Type AB Genotype AB
Blood Type O Genotype OO
The alleles A and B exhibit a greater dominance than O. This is the reason why the Parent of Blood type A will form the Genotype AO.
3 specific tasks you must do while working with Professor Ingo Potrykus on this specific project is plant hybridization, growth recognition and quality of the products obtained.
<h3>How is lineage improvement done?</h3>
The answer is to obtain populations with genetic variability. This can be achieved through hybridization or crossbreeding. Hybridization is the fusion of genetically different gametes, which results in hybrid individuals heterozygous for one or more loci.
With this information, we can conclude that 3 specific tasks you must do while working with Professor Ingo Potrykus on this specific project is plant hybridization, growth recognition and quality of the products obtained.
Learn more about plant hybridization in brainly.com/question/1448528
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