In the economics and big business area from President Wilson Term we can point out:
He created The Underwood-Simmons Tariff in order to achieve a tariff reform. He advocated high tariffs were damaging US economy and creating monopolies. He argued against the lobby that have been working only for the big companies and big businesses, and by doing that gained popular agreement. He could lowered the tariffs, something never achieved since the Civil war.
He created The Federal Reserve Act of 1913 producing a new national banking system, with regional reserve banks controlled by a central board of directors.
As a result of the continuing Giant corporation's growth, despite the Sherman Anti-trust Act, he decided to make a strong Federal Trade Commission (FTC) to be the foundation of his anti-trust program.