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lbvjy [14]
3 years ago
14

Our Account

Medicine
1 answer:
bezimeni [28]3 years ago
8 0

Specifics from the scenario

Lasix is prescribed along with Accupril to the hypertensive patient because;

  • High blood pressure reading of 150/92 in spite of being on the antihypertensive Accupril for the past four months
  • Bilateral lower extremity edema.  

Explanation:

Blood pressure medications which act as calcium channel blockers like Accupril will widen the constricted blood vessels to allow for more blood and fluid to flow easily.

This sometimes leads to an excess amount of fluid in the circulatory system which gets accumulated in the lower extremities. This leads to edema of the feet, especially in the ankle region.  

To treat this fluid accumulation in the feet, a diuretic class drugs are prescribed as an adjuvant. Loop diuretics like Lasix (furosemide) act by lowering the blood pressure as well as reducing the fluid content by increased urine output.

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The acidic urinary pH increases the formation of uric acid or cysteine crystals. Therefore, kidney stones are very much influenced by urinary pH. More acidic urine and a higher frequency of uric acid stones have been associated with patients with inadequate ammonium excretion of metabolic syndrome.

Kidney stone disease results from deficiencies in urinary acidification, which result in the excretion of improperly alkaline or acidic urines, respectively. Patients with uncommon mendelian kidney stone variants have mutations in several enzymes, transporters, receptors, or channels. Numerous of these alterations either result in an increase in the excretion of chemicals that can crystallise or stone, a change in the composition of the urine that promotes crystal formation, or both.

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