When Alexander took the throne, he vowed to complete the plans of his father. After three grueling years of warfare, Alexander smashed the Persian armies at the Tigris River and conquered the Persian Empire. While fighting the Persians, Alexander conquered Egypt and founded a city at the mouth of the Nile River (Alexandria). He continued his campaign until he reached India and the Indus River. Where his exhausted troops refused to fight further. And without the support of his army, Alexander had to turn back and begin consolidating his empire.
God called upon Abraham as God found a new nation in an undesignated land that he later learned was Canaan. The known children of Abraham would be Isaac, son of Abraham and Sarah. The last question is more of a personal question, how you feel about it.