A. Brutus and Cassius are defeated at Philippi, making Antony and Octavius the leaders of Rome.
The final act ends up with Cassius and Brutus fighting against Antony and Octavius. Both Cassius and Brutus end up dying and that solidifies that Antony and Octavius will rule, although the play does hint at potential friction between the two remaining leaders.
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The Spanish conquistadors were explorers from Spain that came to the Americas and basically took over many parts of it. Hernando Cortez brought a sickness to the Aztecs, which killed them all. Francisco Pizarro conquered the Inca empire. They are both examples of Spanish conquistadors.
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The answer is definitely D.
MIT defines calculus as the study of change, usually in motion.