The expression "coked to the gills" is an expression that means the person is very intoxicated, either on alcohol or illegal drugs.
Answer: but where is the text?
<span>If one has poor physical health, for example, obesity, the individual may spend more time living a sedentary lifestyle. Those who live with this type of lifestyle spend more time indoors, playing video games, watching tv or playing on their phones. By isolating ones self from social contact there are more incidences of depression, anxiety, and panic disorders. Individuals who regularly go to the gym, grocery store or hang out with friends have shown to have a lesser prevalence rate of mental health disorders as well has lesser physical health issues. A sedentary lifestyle can also lead to numerous other health issues such has heart disease, cardiovascular disease, various types of cancers and lung diseases.</span>
<span>The only place for the topic sentence is in the beginning as its purpose is to attract readers so that they would like to read a work till the end. So, to answer your question, the topic sentence should never be in the last lines, where the conclusion <span>of the whole work is written.</span></span>