<span>The majority of successful works of fiction, whether short or long, tend to have plots based on conflict and resolution. The main exception to this is a genre known as the picaresque, which follows the exploits of a colorful protagonist (a "picaro") through a series of (often comic or adventurous) episodes. Conflict and resolution, and often a desire to see how a conflict will be resolved, are key features which motivate a reader to move through a story from start to finish. They form a structural skeleton around which the edifice of a work is constructed; without this structure, many stories would just ramble on pointlessly.</span>
I believe it is option "D.) The flu vaccine is not reliable enough to be worthwhile" It would have a negative impact on the economy due to people not spending money to have the flu vaccine.
