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According to the internet, the Friar is referring to Juliet's parent that them crying is normal and natural, but since Juliet is in a better place, they should rejoice for the dead and that her soul is still pure when she goes up to heaven because she is young.
Or,
Natures tear meaning natural tears, merriment meaning happy. It is natural to cry over the death of a child but they should be happy she is going to be in a better place.
This is where Lennie has gone back to that place by the river after he has killed Curley’s wife. Lennie expects that George will give him hell. he asks George if George is not going to do it. George says that he will not, but Lennie really wants him to.