Answer: Solution 2 because the single substrate easily get transformed into products at the active site of any of the 100 enzymes.
Explanation:
Since Solution 1 has 1 enzyme to 100 substrate while Solution 2 has 100 enzyme to 1 substrate, catalysis of the single substrate to product will be greater in Solution 2 as the enzyme will compete to quickly transform the single substrate in its active site unlike solution 1 will 100 substrates taking more time.
One way valves maintain the unidirectional flow.
He forgot to state the problem
I think it is D.... hope i'm right
