The Lock-and-key mechanism was first proposed by Emil Fischer which described as the enzymatic reactions whereby an enzyme with a single substrate binds temporarily to form a substrate complex.
The lock-and-key mechanism is usually associated with the complementary shapes of an enzyme with a single substrate, wherein the lock that is being referred to is the enzyme and the substrate is the key. One right sized substrate (key) fits into the active site (key hole) of the enzyme (lock).
The active site which is mentioned above is structurally complementary to the substrate. This is the temporary binding site on the enzymes. Just like a lock and key, the enzyme as the lock and the substrate as the key is said to fit together.
No, I am not preparing for a medical entrance exam
Cellular respiration occurs in animals and plants
Answer:
systemic lupus erythematosus
Explanation:
Systemic lupus erythematosus (SLE or just lupus) is a chronic inflammatory disease of autoimmune origin, the symptoms of which may appear in various organs slowly and progressively (in months) or more rapidly (in weeks) and vary with phases of activity and remission. Because it is a disease of the immune system, which is responsible for producing antibodies and organizing inflammation mechanisms in all organs, when a person has SLE they may have different types symptoms and various body locations. Some symptoms are general such as fever, weight loss, loss of appetite, weakness and discouragement. Others, specific to each organ such as joint pain, skin blemishes, pleural inflammation, hypertension, and / or kidney problems.
The main cause of this disease is the imbalance in the production of antibodies that react with proteins in the body itself and cause inflammation in various organs such as the skin, mucous membranes, pleura and lungs, joints, kidneys, etc.). Thus, we understand that the type of symptom a person develops depends on the type of autoantibody the person has, and that as the development of each antibody relates to the genetic characteristics of each person, each person with lupus tends to have clinical manifestations. specific and very personal (symptoms).
Autoantibodies are antibodies directed to the body's own cells and tissues. Normally, the immune system differentiates the body's own proteins from foreign proteins, forming antibodies only against those identified as potentially dangerous.
