Answer:
B: madness, insanity, and murder.
Explanation:
The Tell-Tale Heart was a short story written by Edgar Allan Poe in 1843 which had the major themes like; madness & insanity, guilt, effect of time on his psyche all tending towards topic of killings/murder.
Looking at the options given, the correct one is Option B.
It could be both, maybe they hurt themselves because they want to call some attention or it could also be their way to feel better with themselves