In the following orbital the lone pair on each N atom is present:
N1: sp3,
N2: p,
N3: p,
N4: sp2,
N5: sp2
Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.
The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.
The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.
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Aliskiren was added to enalapril in individuals with chronic heart failure, however there was no improvement in the side effects in hypertension. In comparison to enalapril, noninferiority was not demonstrated for aliskiren.
Antihypertensive medications like enalapril have varying effects on blood pressure regulation, so for a synergistic effect, these medications are typically combined. Ninety percent of hypertension patients have an unknown underlying etiology. As a result, the primary function of antihypertensive medications such as enalapril is to change the body's regulatory systems (such as the renin-angiotensin-aldosterone system and baroreceptors) in order to maintain normal blood pressure. Enalapril at a dose of 5 or 10 mg twice daily for 2336 patients, aliskiren at a dose of 300 mg once daily for 2340 patients, or both therapies for 2340 patients of hypertension, to one of three groups (combination therapy). Heart failure hospitalization or death from cardiovascular causes made up the majority of the composite outcome in hypertension.
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Answer:
It can cause a wide range of health issues.
Explanation:
Weight gain, trouble sleeping, anxiety, depression, headaches, GI problems like constipation and diarrhea, easy bruising, muscle weakness and increases cholesterol, and blood pressure.
Answer:
The formula is designed to provide similar amounts of calories as breast milk would provide.
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Answer:
The best answer to the question: When the corpus luteum degenerates:___, would be, E: All of the above.
Explanation:
The process of human female reproduction is a very complex one. But center in it is the corpus luteum, a structure that develops from a follicle in the ovaries and which will be responsible for producing estrogens and progesterones to maintain pregnany in case there is egg fertilization, or, the dismantling of everything by decaying and thus stopping the outpour of these gonadal steroids. When fertilization occurs, the corpus luteum, by producing estrogen and progestorone, inhibits the further production of LH and FSH, and thus the entire process for a successful pregnancy takes place. But when this does not occur, LH and FSH increase again, progesterone, most especially, decreases, and as a result, the endometrium, which had been prepared for implantation, sloughs off. This is why the answer is E.
