Mesoamerica is a historical region and cultural area in North America. It extends from approximately central Mexico through Belize, Guatemala, El Salvador, Honduras, Nicaragua, and northern Costa Rica. Within this region pre-Columbian societies flourished for more than 1000 years before the Spanish colonization of the Americas. Mesoamerica was the site of two of the most profound historical transformations in world history: primary urban generation, and the formation of New World cultures out of the long encounters among Indigenous, European, African and Asian cultures.lanation:
The main reason why the Spanish built the St. Augustine fort in Florida was "to protect their sea route to the Caribbean" since this was a crucial port for many engaged in trade within the Caribbean.