Answer: FIRST OPTION.
Step-by-step explanation:
For this exercise it is important to remember a property called "Quotient of Powers property".
By definition the Quotient of Powers property states the following:

You can observe the division of
and
. Since both have the same base "a" , you must rewrite the base and subtract the exponents "m" and "n".
In this case, you have the following expression given in the exercise:

Then, you need to apply the Quotient of Powers property rewriting the base 4 and subtracting the exponents 12 and 5.
Therefore, you get the following result:

You can notice that it matches with the first option.