<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
ANSWER:
A
Explanation: chimpanzees have 0% difference from humans.
Difference threshold is a minimum alteration in sensory intensity that is noticeable to an observer and can be coded into neural messages. Different threshold is the lowest level of encouragement that is essential to sense that a modification has happened the difference in the intensity between two stimuli that is necessary to yield a just notable difference also known as JND. The just notable difference depends not only on the intensity of the new stimulus but also on the level of stimulation already present which is the more intense the existing stimulus the larger the change must be to be noticeable.
