One of Josephine Baker’s most famous professional tasks was tracking down Mary Mallon (“Typhoid Mary”) in 1907. The way Ms. Mallon’s case was handled raises some interesting questions even today about conflicts between personal rights and public health: George Soper at the Department of Health Laboratories had investigated seven family epidemics of typhoid going back to 1900. He found that they were all linked to the cook [Mary Mallon] in each family.
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isolation
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China was one of the first civilizations in the world. This civilization, unlike the others, was actually very isolated from the rest of the ancient civilizations. The main reason for the isolation were the natural barriers. Between China and the other civilizations were standing the largest mountain range in the world, the Himalayas, and several large deserts. This discouraged people both from China and from the other civilizations from moving through this areas and see what's on the other side. This resulted in developing a very unique culture in China that was not influenced by any other culture. Also, this civilization was developing totally independently, and it actually managed to surpass the other civilizations in many aspects, while they were not even aware of its existence, or just knew that it existed but had no real idea about it. China only opened up properly to the world after it was invaded and ruled by the Mongols.
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The so-called Age of Exploration was a period from the early 15th century and continuing into the early 17th century, during which European ships were traveled around the world to search for new trading routes and partners to feed burgeoning capitalism in Europe.