The correct answer to this open question is the following.
Colonies were paired together in different regions based on geography and climate.
The New England colonies were Connecticut, Rhode Island, Massachusetts Bay, and New Hampshire. They did not have fertile soil. It was rocky soil. They better developed fishing techniques. The Middle colonies were New York, New Jersey, Pennsylvania, and Maryland. The had good and fertile soil to grow crops. They were called the bread-basket of America for the kind of crops they produced. Virginia and Maryland were colonies that specialized in growing Tobacco. The Southern colonies were North Carolina, South Carolina, Georgia, and Florida.
For in the beginning the Indians regarded the Spaniards as angels from Heaven. Only after the Spaniards had used violence against them, killing, robbing, torturing, did the Indians ever rise up against them.