The Holy Roman Empire was completely destroyed.
This is probably biological warfare because it's not allowed according to the Geneva congress. Using poisons, toxic matters, viruses and bacteria, as well as flamethrowers and things like that are forbidden or else it will be considered a war crime and people will answer for it. It was practiced in World War 1 but was forbidden after.
They where based on human reason, they believed that humans had wisdom.
Also adopt nearing after seeing voilence
