Lost their jobs, homelessness increased, people went hungry
One item can be the weapons. Many Europeans gave the natives a bunch of weapons because they had plenty. They even gave them faulty weapons or broken ones because the natives didn't know any better.
Answer:
They earned money from colonization, so it mainly became a battle of how rich they were. And then the exploration part pretty much meant that they could claim 'new' land (that was already pretty much discovered by Native Americans) and make even more money, along with having power in the New World.
Explanation: