The answer is 2001 because the region is part of the racism
Well, I can tell you for sure that a is not the answer. But I think the answer would be b.
In the 1800s the Great Plains region of the United States was characterized by: Vast expanses of native grasses.
You can consider it to be Isolated. The doctrine was about preventing anyone from Europe from participating in political activities in the new land, and it was proclaimed that any European force that tried to control or colonize countries in the new land would be considered to be unfriendly to the US and the US would help the countries under attack.
The Limpopo river separates Botswana and South Africa