A dumping site in the small town of Love Canal, New York, was used for the disposal of industrial chemical wastes from 1970-1975
. In 1980, the housing inspector noticed traces of toxic substances in the basement walls of the local schools and homes. The local hospital noticed that there were 25% higher numbers of birth defects during 1970-1980. The hospital then offered free genetic tests and found that 20% of the adult volunteers/residents of Love Canal contained genetic abnormalities. The exposure to those industrial chemical wastes must have been the cause the genetic abnormalities and higher birth defect incidence. Your Interpretation:
There is no control group and variables were not addressed.
Explanation:
In the context, it is given that there is a dumping ground in a small town called Love Canal and harmful chemical waste of industries are dumped there. Lately, it is noticed that there were traces of the toxic substances on the walls of the schools and the hospitals. The hospitals also noticed that during the period of 1970 to 1980, there were increase in the number of the birth defects in the area. The people of the Love Canal has genetic abnormalities and the chemical waste is responsible for it.
Thus it can be concluded that there is a no such any control group in this case. The confounding variables like the comorbidities as well as the family history of the genetic defects were not addressed.
Structural organization of nucleosomes were determined by isolating them from unfolded chromatin and it has been found that the basic units of chromatin are the nucleosomes which consist of histone octamers of two molecule each of histone H2A and other histone molecules like H2B, H3 and H4. The histones are wrapped around with 147bp of DNA in almost two (2) turns.
