Answer:
Your answer is (number 4)
Explanation:
The arrival of Spanish Conquistadors is the main cause for the downfall of both Inca and Aztec empires.
While C and D are both true, C caused them to suffer most greatly.
<span>The Mixtec, another important civilization that existed at the same time as the Mayans, created the most elaborate codices of all the Mesoamerican civilizations. They used deerskin instead of bark cloth or vegetable fiber.</span>