The excerpt from Lord Byron's Childe Harold's pilgrimage that most clearly describes a state of alienation is the third one:
C. But soon he knew himself the most unfit / of men to herd with man.
He says here that he isn't the type to be around other people, which is why he prefers to be around himself only. Although that doesn't mean he doesn't like or want to be around other people, it is just that he doesn't know how to and is thus alienated.
The effect is what the workers do and when they do it
C would be the most likely answer here.
