Answer:
The tiles can be arranged as follows:
- make an observation
- ask questions
- construct a hypothesis
- test the hypothesis
- analyze the results and make conclusions
- communicate the result
Explanation
A scientific investigation begins with certain observations. By seeing these observations, a question is made. To answer the question, a hypothesis is generated. A hypothesis is a tentative statement that can either be stated s correct or wrong. To test the hypothesis, experiments are made and results are deduced from the experiments. Based on these results, a hypothesis can be proved as correct or wrong. These results are then communicated to check for their authenticity.
Answer:
The correct insulin pathway is described as under:
2. Binding of insulin to the alpha subunit of the insulin receptor
8. Activation of insulin receptor tyrosine kinase
3. Phosphorylation of IRS proteins
6. Phosphorylation of phosphinositide 3-kinase (PI-3K)
4. Conversion of PIP2 to PIP3
7. Activation of PIP3-dependent protein kinase B (PDK1)
5. Glut4 receptors transported to the cell membrane
Explanation:
The insulin signaling pathway is described as under:
RTK (receptor tyrosine kinases) which is a receptor for insulin is an extracellular receptor but in contrast to other cell surface receptors it is catalytic in nature. In the absence of insulin (ligand), it is monomeric but as soon as it gets activated (activation occurs upon ligand binding), it undergo dimerization. It leads to auto-phosphorylation in it's tyrosine residue which subsequently leads to phosphorylation of tyrosine residue of other receptors. Such hyper-phosphorylated receptor have high affinity with enzyme/molecule like IRS protein which have SH2 domain . IRS down stream activates phosphinositide 3-kinase (PI-3K). This enzyme converts component of animal cell membrane PIP2 into PIP3. PIP3 also remains membrane bound but it has the potential to phosphorylate another enzyme named as PIP3-dependent protein kinase B (PDK1). Further, PDK1 leads to the activation of Akt or PK-B. Akt is a serine-threonine kinase which ultimately leads to the recruitment of Glut4 receptors on cell membrane for uptake of more and more glucose into the cell.
Note: Apart from this Akt also phosphorylates another protein named as FOXO which ultimately causes cell growth, Akt can also phosphorylate BAD protein so as to restrict cell apoptosis or we can say it leads to cell survival, Akt also leads to translation in a cell with the help of mTOR raptor etc.
Answer:
Just before the cat drops, it was stationery. Therefore it has energy of position called potential energy.As it drops, the Gravitational potential energy is converted to Kinetic Energy,The conversion mid- air is P.E to K.E to P.E to K.E to P.E to K.E, until it touches the ground. As it touches the ground all the energy is converted to P.E energy of position.
As it runs after mouse the P.E is converted back to Kinetic , energy of motion. As it feeds on the mouse , the chemical energy obtained as protein from mouse meat.This is later converted back to Mechanical energy as (kinetic and Potential energy) in the cat.
Explanation:
C. because there is a property of acids which stat that they turn litmus papers red instead of blue.
