One of the major ways in which Italian artists used the ideas of the humanist movement in their works is that they focused literally on the human body and mind as opposed to God and the Church--especially in the realm of painting and sculpture.
The answer is majority rule
In the North cold made farming difficult while in the South climate was ideal for agriculture.
Immigration created a huge population increase in the North while 1/3 of the southerners were slaves. Cities in the north developed as centers of trade whereas most southerners lived on farms.
The economy in the North was based on manufacturing differing from the agricultural South.
But the most significant development was transportation. Canals had been built and most of the railroads were in the North. However, the south still depended on steamships.
I'd say "loose nukes"
I think. That's what my history teacher lectured us about yesterday