A. Richard Nixon's tolerance
The Nile River supplied a constant water source and fertile land around it that could be used for farming, which is important because pretty much everywhere else on the African continent is desert
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They helped emperors and kings manage the administration of their empires. They made sure that the laws of the Church and State were obeyed.
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Okay!
So, one of the main similarities between these two cultures is they were both polytheistic (believing in more than 1 god). They believed in gods of certain elements, such as water, sky, etc. They also had passions for arts, astronomy, and other areas.
A difference between these cultures, however, is that Mesopotamia had kings, while Egypt had Pharaohs, seen as literal gods. Another difference was their view of the afterlife, that being Egypt viewed it as a blissful place, while Mesopotamia viewed it as a true hell.
We won't supply a thesis statement for you, since that's something for you to do on your own! =)