Answer:
it is a failure of tolerance (self-tolerance) and specificity (recognition)
Explanation:
Type 1 diabetes is a chronic disease caused by the selective destruction of β cells that are involved in the production of insulin in the pancreas. Type 1 diabetes can be classified into two types: Type 1A diabetes (the immune form of the disease) and Type 1B diabetes (the non-immune form of the disease). Type 1A diabetes is considered an autoimmune disorder where immune responses against pathogens suffer a failure of tolerance to antigens in the β-cells of the pancreatic islets. Thus, Type 1A diabetes is characterized by the process of recognition of β-cell antigens (autoantigens) by the immune system. This disease is often caused by genetic factors associated with mutations in the human leukocyte antigen (HLA) class II region located on chromosome 6.
Things such as coal and oil are limited because they are only found in some places
Explanation:
Variations in the sun's energy reaching Earth
Changes in the reflectivity of Earth’s atmosphere and surface
Changes in the greenhouse effect, which affects the amount of heat retained by Earth’s atmosphere
