About 71 percent of the Earth's surface is water-covered, and the oceans hold about 96.5 percent of all Earth's water. Water also exists in the air as water vapor, in rivers and lakes, in icecaps and glaciers, in the ground as soil moisture and in aquifers, and even in you and your dog. Water is never sitting still.
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In the cell, energetically unfavorable reactions are often coupled with favorable ones, such that the new overall reaction is favorable.