Because the DNA sequence determines a protein's amino acid sequence, a gene shared by two closely related organisms should have similar, or even identical, amino acid sequences. That's because closely related species most likely diverged from one another fairly recently in the evolutionary span. Thus, they haven't had as much time to accumulate random mutations in their genetic codes.
My guess would be H₂O/ water, since osmosis is a form of passive transport and I can't see the model the question references. Gases like O₂/ oxygen, CO₂/ carbon dioxide, and simple sugars like glucose can also pass through a cell membrane with passive transport though.
