It was "Andreas Vesalius" who was the sixteenth-century physician who published the first accurate and detailed picture of human anatomy, since he was one of the most advanced and knowledgeable surgeons of his time
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The westward expansion led to many other events in and around the United States. Before Manifest Destiny and the westward expansion the French and Indian War and Revolutionary War took place which allowed America to declare independence. There's no telling weather its positive or negative, but it leans more on the positive side, because of its impact.
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