Charleston was an incredibly important city in the South because of its location--it was located on a prime piece of coast line that made importing and exporting goods relatively fast and easy.
federal Taxes were too high.
Federal Gov't was too strong and put too many rules in place on states.
Rugged Individualism, that individuals should take care themselves and not rely on Federal Gov't to help (poor) or regulate (rules)
History is true. Or else why would we learn it?