Fibrin is an insoluble component of plasma that forms a meshwork of strands and is considered the structural basis of clot formation.
<h3>What is clot formation?</h3>
- Blood turns from a liquid to a gel during coagulation, which results in the formation of blood clots.
- Possible outcomes include haemostasis, which stops blood loss from a broken vessel, followed by repair.
- The activation, adhesion, and aggregation of platelets, as well as the deposition and maturation of fibrin, are all components of the coagulation process.
<h3>What is fibrin?</h3>
- A fibrous, non-globular protein called fibrin is necessary for blood to clot.
- It is created when fibrinogen undergoes polymerization due to the protease thrombin.
- A haemostatic plug or clot is formed over a wound site by platelets and polymerized fibrin.
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