1. Drawing conclusions
2. Analyzing data
3. Interpreting data
4. Collecting data
5. Reporting data
6. Research data
Assuming you're referring to Theodore Roosevelt, one of the most successful things he did in terms of regulating big business was the "break up the trusts,"--in that he took to court companies that were suspected of colluding with other firms and forming monopolies.
Most early scientists that questioned authority and traditional thought often were challenging the power and beliefs of the Catholic Church. This lead to many being forced into being placed into a house arrest type situtation. Others, who refused to take back, recant, their findings and beliefs were killed.